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KMID : 0363320220430010022
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Journal of Korean Oriental Internal Medicine
2022 Volume.43 No. 1 p.22 ~ p.40
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A Study on the Blood Sugar Improvement Effect and Safety of Galgunhwangryunhwanggum-tang for Type 2 Diabetes without Complications: A Systemic Review and Meta-Analysis
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Shin Jae-Ik
Baek Ji-Soo
Cho Chung-Sik
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Abstract
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Objectives: The purpose of this study is to assess the antidiabetic effect and safety of Galgunhwangryunhwanggum-tang for type 2 diabetes without complications by analyzing related research.
Methods: For a systematic review and meta-analysis, we searched for the antidiabetic effect and safety of Galgunhwangryunhwanggum -tang for type 2 diabetes without complications in 10 databases up to September 2021. Only randomized controlled trials were chosen.
Results: In the treatment effectiveness analysis and meta-analysis, Galgunhwangryunhwanggum-tang had significant improvement effects on fasting plasma glucose level, 2-hour postprandial glucose level, glycated hemoglobin, fasting insulin, and homeostasis model assessment for insulin resistance compared to the control group when treated in parallel with oral glycemic drugs.
Conclusion: Galgunhwangryunhwanggum-tang is effective in improving blood sugar and insulin resistance in type 2 diabetes patients without complications and can especially be considered in parallel treatment with oral hypoglycemic drugs. A large-scale randomized controlled clinical trial is required to complement the limitations presented in this study in the future.
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KEYWORD
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Galgunhwangryunhwanggum-tang, antidiabetic effect and safety, type 2 diabetes without complications, systematic review, meta-analysis
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